4-Methyl-3-nitropyridin-2-amine
نویسندگان
چکیده
In the title compound, C(6)H(7)N(3)O(2), the dihedral angle between the nitro group and the pyridine ring is 15.5 (3)° and an intra-molecular N-H⋯O hydrogen bond occurs. In the crystal, inversion dimers linked by two N-H⋯N hydrogen bonds occur, resulting in R(2) (2)(8) rings. The packing is stabilized by aromatic π-π stacking [centroid-centroid distance = 3.5666 (15) Å] and a short N-O⋯π contact is seen.
منابع مشابه
2-Chloro-5-nitropyridin-4-amine
The title mol-ecule, C(5)H(4)ClN(3)O(2), possesses mirror symmetry, with all of the atoms lying in the mirror plane. There is an intra-molecular N-H⋯O hydrogen bond involving the adjacent -NO(2) and -NH(2) groups. A short C-H⋯O inter-action is also observed. In the crystal, adjacent mol-ecules are linked via N-H⋯Cl and N-H⋯N hydrogen bonds, forming chains propagating along [100].
متن کاملN-(4-Chlorophenyl)-3-nitropyridin-2-amine
In the title compound, C(11)H(8)ClN(3)O(2), the presence of intra-molecular N-H⋯O and C-H⋯N inter-actions help to establish an almost planar mol-ecule [dihedral angle between the pyridine and benzene rings = 9.89 (8)° and r.m.s. deviation for all 17 non-H atoms = 0.120 Å]. Supra-molecular tapes feature in the crystal packing whereby dimeric aggregates sustained by pairs of C-H⋯O inter-actions a...
متن کاملN-(4-Methylphenyl)-3-nitropyridin-2-amine1
Two independent mol-ecules comprise the asymmetric unit of the title compound, C(12)H(11)N(3)O(2). These differ in terms of the relative orientations of the benzene rings as seen in the respective dihedral angles formed between the pyridine and benzene rings [17.42 (16) and 34.64 (16)°]. Both mol-ecules are twisted about the amine-tolyl N-C bonds [respective torsion angles = 22.3 (5) and 35.9 (...
متن کاملCrystal structure of a new monoclinic polymorph of N-(4-methylphenyl)-3-nitropyridin-2-amine
The title compound, C12H11N3O2, is a second monoclinic polymorph (P21, with Z' = 4) of the previously reported monoclinic (P21/c, with Z' = 2) form [Akhmad Aznan et al. (2010 ▶). Acta Cryst. E66, o2400]. Four independent mol-ecules comprise the asymmetric unit, which have the common features of a syn disposition of the pyridine N atom and the toluene ring, and an intra-molecular amine-nitro N-H...
متن کامل(R)-(+)-2-{[(3-Methyl-4-nitropyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole1
The title compound, C(14)H(12)N(4)O(3)S, is an inter-mediate of Dexlansoprazole, a proton pump inhibitor (PPI) mainly developed for anti-ulcer activity. The absolute configuration of the title compound was determined as R. The crystal structure reveals that the mol-ecules form chains along the b axis through N-H⋯N and C-H⋯O hydrogen-bonded dimers. These chains are connected via weak C-H⋯O hydro...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 65 شماره
صفحات -
تاریخ انتشار 2009